Retatrutide (5mg | 10mg | 15mg | 20mg | 30mg | 40mg | 50mg | 60mg)

Price range: £44.99 through £289.99

Retatrutide is being studied for potentially beneficial effects across weight management, glucose regulation and broader cardiometabolic health. As a triple agonist targeting GLP-1, GIP and glucagon receptors, it is designed to influence appetite, satiety, glucose control and energy metabolism through multiple pathways. Clinical trials have reported substantial reductions in body weight. In a Phase 2 obesity trial, participants receiving the highest studied dose lost an average of 24.2% of body weight at 48 weeks. More recent Phase 3 results reported average weight loss of up to 28.3% at 80 weeks in adults with obesity or overweight without diabetes.

Description

Retatrutide is an investigational triple-receptor agonist designed to activate GLP-1, GIP and glucagon receptors. It has attracted significant research interest because these three signalling pathways are involved in appetite regulation, glucose metabolism, energy expenditure and body-weight regulation.

Retatrutide is being studied primarily in relation to weight reduction and metabolic health. Clinical research has examined its potential effects on appetite suppression, satiety, body-weight reduction, glucose control, insulin sensitivity and cardiometabolic risk markers.

Its glucagon-receptor activity also makes it of interest for research into energy expenditure and lipid metabolism, distinguishing it mechanistically from single- and dual-incretin agonists such as semaglutide and tirzepatide.

Research areas include:

  • Body-weight regulation and appetite signalling
  • Glucose metabolism and insulin sensitivity
  • Energy expenditure and metabolic efficiency
  • Lipid and fat metabolism
  • Cardiometabolic risk factors
  • Obesity and related metabolic conditions

Tides Retatrutide is supplied as a lyophilised research-grade powder, with independent batch testing used to verify identity and purity.

Product information:

  • Retatrutide
  • GLP-1/GIP/glucagon receptor agonist
  • Lyophilised powder
  • Purity >99%
  • Independently batch tested
  • Certificate of Analysis available
  • UK dispatched
  • For research use only

Additional information

Size (mg)

5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 100mg, 120mg

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